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. 2018 Sep 7;16(9):318. doi: 10.3390/md16090318

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of caulerpin (CLP) treatment on the Disease Activity Index (DAI) after DSS-colitis induction. The development of colitis was assessed by the DAI, which considers animal weight loss, presence of blood in the stool, and stool consistency. The data are representative of three independent experiments. (A) Disease activity index, (B) body weight (%), (C) bleeding score, and (D) stool consistency score. Each point represents the mean ± SD from the tested animals. The data are representative of three independent experiments, with five animals per group in each experiment (N = 5). ### p < 0.001, ## p < 0.01 and # p < 0.05, vehicle + water versus vehicle + 3% DSS. *** p < 0.001, ** p < 0.01 and * p < 0.5, vehicle + 3% DSS versus CLP 4 mg/kg + 3% DSS.