. 2018 Aug 2;7(3):69. doi: 10.3390/antibiotics7030069

Table 2.

Bacteria-mediated AgNPs biosynthesis and their activity against MDRB.

Bacteria	AgNPs Size (nm)	Target MDR Microorganism	Test Type ^a	Test Result ^b	Reference
Streptomyces	20–70	K. pneumoniae (ATCC 100603)	MIC	4 μg mL⁻¹	[92]
		K. pneumoniae	MIC	1.4 μg mL⁻¹
		E. coli	MIC	2 μg mL⁻¹
		Citrobacter	MIC	2 μg mL⁻¹
Bacillus sp.	14–42	S. epidermidis strain 73 (pus)	ZI	15 mm	[93]
		S. epidermidis strain 145 (catheter tips)	ZI	19 mm
		S. epidermidis strain 152 (blood)	ZI	19 mm
		S. aureus (MTCC 87)	ZI	18 mm
		S. typhi	ZI	13 mm
		S. paratyphi	ZI	15 mm
		V. cholerae (MTCC 3906)	ZI	18 mm
Bacillus cereus	24–46	E. coli	MIC, ZI	6.25 μg mL⁻¹ (MIC), 16 ± 1 mm (ZI)	[94]
		S. aureus	MIC, ZI	12.5 μg mL⁻¹ (MIC), 14 ± 1 (ZI)
		K. pneumoniae	MIC, ZI	>3.12 μg mL⁻¹ (MIC), 17 ± 1 mm (ZI)
		P. aeruginosa	MIC, ZI	3.12 μg mL⁻¹ (MIC), 23 ± 1 mm (ZI)
Bacillus safensis (LAU 13)	5–95	E. coli	ZI	11–19 mm	[95]
		K. granulomatis	ZI	11–19 mm
		P. vulgaris	ZI	11–19 mm
		P. aeruginosa	ZI	11–19 mm
		S. aureus	ZI	11–19 mm
Aeromonas sp. THG-FG1.2	8–16	B. cereus (ATCC 14579)	ZI	13.5 ± 0.5 mm	[88]
		B. subtilis (KACC 14741)	ZI	13 ± 1.0 mm
		S. aureus (ATCC 6538)	ZI	15.5 ± 0.5 mm
		E. coli (ATCC 10798)	ZI	13 ± 0.2 mm
		P. aeruginosa (ATCC 6538)	ZI	16 ± 0.1 mm
		V. parahaemolyticus (ATCC 33844)	ZI	16 ± 0.1 mm
		S. enterica (ATCC 13076)	ZI	11 ± 0.2 mm
		C. albicans (KACC 30062)	ZI	20 ± 0.1 mm
		C. tropicalis (KCTC 7909)	ZI	15 ± 0.5 mm
Bacillus thuringiensis	15	E. coli	ZI	12 ± 1 mm (*)	[96]
		P. aeruginosa	ZI	16 ± 1 mm (*)
		S. aureus	ZI	9 ± 1 mm (*)
Anabaena diololum	10–50	K. pneumoniae DF12SA (HQ114261)	ZI	36 ± 0.82 mm	[97]
	10–50	E. coli DF39TA (HQ163793)	ZI	33 ± 1.63 mm
	10–50	S. aureus DF8TA (JN642261)	ZI	34 ± 0.81 mm
Streptomyces sp. GUT 21	23–48	E. coli (MTCC 9537)	MIC, ZI	14 μg mL⁻¹ (MIC), 27.05 ± 3.20 mm (ZI)	[89]
		K. pneumoniae (MTCC 109)	MIC, ZI	12 μg mL⁻¹ (MIC), 28.50 ± 2.60 mm (ZI)
		S. aureus (MTCC 96)	MIC, ZI	15 μg mL⁻¹ (MIC), 24.25 ± 2.09 mm (ZI)
		P. aeruginosa (MTCC 1688)	MIC, ZI	10 μg mL⁻¹ (MIC), 10.05 ± 3.60 mm (ZI)
Bacillus megaterium	80–98.56 (AFM)	S. pneumoniae	ZI	21 mm	[98]
Bacillus megaterium	80–98.56 (AFM)	S. typhi	ZI	18 mm	[98]
Xanthomonas spp.	5–40	P. aeruginosa	ZI	10.0 ± 1.0 mm	[91]
Xanthomonas spp.	5–40	baumannii	ZI	10.6 ± 0.6 mm	[91]
Sinomonas mesophila MPKL 26	4–50	S. aureus	ZI	12 mm	[90]
Bacillus flexus	12–65	E. coli	ZI	11.55 mm	[99]
		P. aeruginosa	ZI	11.05 mm
		S. pyogenes	ZI	11.65 mm
		subtilis	ZI	11.55 mm
Bacillus brevis (NCIM 2533)	41–68	S. aureus	ZI	19 mm	[100]
Bacillus brevis (NCIM 2533)	41–68	S. typhi	ZI	7.5 mm	[100]

^a ZI = zone of inhibition; MIC = Minimum Inhibitory Concentration; MBC = Minimum Bactericidal Concentration; ^b For tests in which more than one concentration of AgNPs was used, the best results are shown; (*) Values estimated from graphs.