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. 2018 Sep 7;19(9):2660. doi: 10.3390/ijms19092660

Figure 6.

Figure 6

UPM-induced effects on cell proliferation and ROS production in HaCaT cells. (A) HaCaT cells were treated with the indicated concentrations of UPM and then incubated for two days in the presence of the indicated concentration of inhibitors. The results were verified using three independent experiments, each of which was conducted in duplicate. * p < 0.05 vs. the untreated control, o p < 0.05 vs. the UPM-treated control. The data are expressed as the mean ± SD. (B) HaCaT cells were treated with UPM (200 ppm) and then incubated for two days in the presence of the indicated concentration of inhibitors. ROS production was evaluated using 2’,7’-dichlorofluorescein diacetate. UPM, urban particulate matter; SB, SB203580; SP, SP600125; PD, PD98059; PDTC, ammonium pyrrolidinedithiocarbamate; TBHP, tert-Butyl hydroperoxide.