AUC |
Area under the curve |
Cl |
Clearance |
Cmax
|
peak plasma concentration |
DAPI |
4′,6-diamidino-2-phenylindole |
E.E. |
encapsulation efficiency |
Fr |
relative oral bioavailability |
FRA |
fraction of resveratrol absorbed |
FRD |
fraction of resveratrol released |
IVIVC |
In vitro-in vivo correlations |
LR-NP |
Lumogen red-loaded casein nanoparticles |
MRT |
mean residence time |
NP-C |
empty casein nanoparticles |
NP-NOTA-Ga |
casein nanoparticles radiolabeled with Gallium-67 |
PCS |
photon correlation spectroscopy |
PDI |
polydispersity index |
PEG |
polyethylene glycol 400 |
Rsv |
resveratrol |
Rsv-IV |
resveratrol solution intravenously administered |
Rsv-NP-C |
resveratrol-loaded casein nanoparticles |
Rsv-Sol |
solution of resveratrol in a mixture of PEG 400 and water |
Rsv-Susp |
aqueous suspension of resveratrol |
SGF |
simulated gastric fluid |
SIF |
simulated intestinal fluid |
t1/2
|
half-life of the terminal phase |
Tmax
|
time to reach plasma concentration |