Figure 1.

(A) Skeletal muscle biopsies of JDM patients express significantly higher levels of OAS genes family: OAS1, OAS2, OAS3, and OASL expression levels were significantly upregulated (p < 0.00001) in MBx of JDM patients compared to healthy controls. (B) Furthermore, OAS gene family expression was positively correlated with each other in JDM MBx. Dataset accession number GSE3307. Data are expressed as log₂ intensity expression levels and presented as vertical scatter dot plots. p values < 0.05 were considered to be statistically significant (* p < 0.05; ** p < 0.005; *** p < 0.0005; **** p < 0.00005).