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Lymphangiogenesis occurs in renal and peritoneal fibrosis. Lymphangiogenesis was observed in a human diabetic nephropathy case and in a rat diaphragmatic fibrosis model induced by chlorhexidine gluconate (CG) by immunohistochemistry. D2-40 and lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) are lymphatic markers. Arrowheads indicate lymphatic vessels. Scale bars = 100 μm.
