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. 2018 Aug 22;7(3):79. doi: 10.3390/antibiotics7030079

Table 1.

Antibacterial activity of silver ions in combination with antibiotics.

Antibiotics Organism Culture Condition Effects References
ß-lactams Ampicillin E. coli Laboratory medium 10-fold increase in antimicrobial activity [3]
Quinolones Ofloxacine, Nalidixic Acid, Norfloxacin E. coli Laboratory medium 10-fold increase in antimicrobial activity. MIC value decreased 10–25% [3,4]
Aminoglycosides Gentamicin E. coli Laboratory medium. Animal models 100-fold increase in antimicrobial activity. MIC value decreased more than 10-fold [3,4]
C. difficile Laboratory medium MIC value decreased 4-fold [4]
Tobramycin E. coli., P. aeruginosa Laboratory medium MIC value decreased 10-fold (E. coli). 3-fold increase in antimicrobial activity (P. aeruginosa) [4,23]
Kanamycin Streptomycin E. coli Laboratory medium MIC value decreased more than 10-fold [4]
Spectinomycin E. coli Laboratory medium MIC value decreased 2-fold [4]
Vancomycin E. coli Laboratory medium. Animal models 10-fold increase in antimicrobial activity [3]
Chloramphenicol E. coli Laboratory medium MIC value decreased 1.5-fold [4]
Ebselen K. pneumoniae, A. baumanni, P. aeruginosa, E. cloacae, E. coli Laboratory medium. Animal models 10-fold increase in MIC value [20]
Polymixin B E. coli Laboratory medium MIC value decreased 5- to 10-fold [21,22]
Rifampicin A. baumannii Laboratory medium MIC value decreased 5-10 fold [21]
Tetracycline E. coli (TetR) Laboratory medium MIC value decreased 2-fold [3]