Table 2.
Characteristics of individuals treated with non-steroidal anti-inflammatories (NSAID) or NSAID and proton pump inhibitors and concomitant drugs at a high risk of gastrointestinal events.
| People Treated with NSAID without PPI | People Treated with NSAID and PPI | p-Value | |
|---|---|---|---|
| Number of individuals | 1381 | 690 | |
| Gender, n (%) | |||
| Male | 1278 (92.5) | 665 (96.4) | |
| Female | 103 (7.5) | 25 (3.6) | |
| Age groups, n (%) | |||
| <50 years | 320 (23.2) | 82 (11.9) | <0.001 |
| 50–54 years | 268 (19.4) | 113 (16.4) | |
| 55–59 years | 482 (34.9) | 273 (39.5) | |
| >59 years | 311 (22.5) | 222 (32.2) | |
| Concomitant medical therapy, n (%) | |||
| Anticoagulant drugs | 15 (1.1) | 25 (3.6) | <0.001 |
| Platelet aggregation inhibitors | 47 (3.4) | 78 (11.3) | <0.001 |
| Corticosteroids | 17 (1.2) | 23 (3.3) | 0.001 |
| SSRI | 33 (2.4) | 24 (3.5) | 0.150 |