Table 4.
Associations a between trimester-specific atrazine concentrations (µg/L) and SGA, term LBW, VLBW, PTB and VPTB among AMP communities (n = 22) in Ohio, 2006–2008.
| Outcome | Model | n | OR g (95%CI) |
|---|---|---|---|
| First Trimester | |||
| SGA b | Crude | 14,022 | 1.02 (0.95, 1.09) |
| Adjusted | 14,022 | 1.04 (0.98, 1.11) | |
| Term LBW c | Crude | 12,647 | 1.14 (1.01, 1.28) |
| Adjusted | 12,647 | 1.20 (1.08, 1.34) | |
| VLWB d | Crude | 14,170 | 1.09 (0.86, 1.37) |
| Adjusted | 14,170 | 1.07 (0.86, 1.34) | |
| PTB e | Crude | 14,179 | 1.01 (0.90, 1.13) |
| Adjusted | 14,179 | 0.99 (0.90, 1.10) | |
| VPTB f | Crude | 14,432 | 1.11 (0.81, 1.53) |
| Adjusted | 14,432 | 1.11 (0.81, 1.53) | |
| Second Trimester | |||
| SGA a | Crude | 14,002 | 0.97 (0.93, 1.00) |
| Adjusted | 14,002 | 0.99 (0.96, 1.02) | |
| Term LBW | Crude | 12,647 | 1.06 (0.98, 1.14) |
| Adjusted | 12,647 | 1.13 (1.07, 1.20) | |
| VLWB | Crude | 14,148 | 0.79 (0.55, 1.14) |
| Adjusted | 14,148 | 0.76 (0.51, 1.13) | |
| PTB | Crude | 14,156 | 0.99 (0.95, 1.04) |
| Adjusted | 14,156 | 0.99 (0.95, 1.04) | |
| Third Trimester | |||
| SGA a | Crude | 12,648 | 0.98 (0.87, 1.10) |
| Adjusted | 12,648 | 1.00 (0.93, 1.08) | |
| Term LBW | Crude | 12,647 | 0.97 (0.80, 1.16) |
| Adjusted | 12,647 | 1.03 (0.87, 1.22) |
a All adjusted models included maternal race/ethnicity, maternal age, and birth year a priori. b Small for gestational age defined as the smallest 10% of infants, according to birth weight, at each gestational age in the population. In addition to a priori variables, the final model for SGA included maternal education, WIC status, marital status, and maternal pre-pregnancy BMI. c Term low birth weight is defined as <2500 g among term births (≥37 weeks gestation). In addition to a priori variables, the final model for term LBW included infant sex, maternal education, WIC status, marital status, maternal smoking status, and maternal pre-pregnancy BMI. d Very low birth weight is defined as <1500 g at time of delivery. In addition to a priori variables, the final model for term LBW included maternal education, marital status, and parity. e Preterm births defined as infants delivered before 37 weeks’ gestation. In addition to a priori variables, the final model for PTB included maternal education, maternal smoking status, and parity. f Very preterm births defined as infants delivered before 32 weeks’ gestation. In addition to a priori variables, the final model for PTB included maternal marital status. g Odds ratios reflect increase in odds per 1 µg/L increase in atrazine in drinking water.