Table 2.
Bone turnover markers according to the use of calcitriol in hemodialysis patients.
| Calcitriol Use in Past Three Months (Total n = 225) | No (n = 81) | Yes (n = 144) | p Value |
|---|---|---|---|
| Wnt 10b (ng/mL) | 2.72 ± 1.26 | 4.13 ± 1.08 | <0.01 ** |
| Wnt 16 (pg/mL) | 44.62 ± 53.84 | 36.76 ± 38.83 | 0.45 |
| β-catenin (ug/mL) | 7.86 ± 5.32 | 8.86 ± 6.26 | 0.20 |
| Sclerostin (pg/mL) | 89.87 ± 59.53 | 72.10 ± 43.12 | 0.06 |
| DKK-1 (pg/mL) | 232.72 ± 449.46 | 142.11 ± 277.62 | 0.03 * |
| Trap5b (U/L) | 10.13 ± 4.04 | 5.57 ± 3.41 | <0.01 ** |
| Free RANKL (pmol/L) | 0.08 ± 0.07 | 0.08 ± 0.07 | 0.997 |
| OPG (pmol/L) | 16.88 ± 6.90 | 16.71 ± 8.56 | 0.58 |
| P1NP (pg/mL) | 43.04 ± 44.27 | 158.87 ± 151.95 | <0.01 ** |
Values are mean ± standard deviation if normally distributed. Value are medians ± interquartile ranges if not normally distributed. Abbreviations: DKK-1: Dickkopf-related protein 1; RNAKL: Receptor activator of nuclear factor kappa-B ligand; Trap5b: Tartrate-resistant acid phosphatase 5b; OPG: Osteoprotegerin; P1NP: Procollagen 1 N-terminal Propeptide. * p < 0.05, ** p < 0.01.