Table 1.
Genome packaging densities in double-stranded ribonucleic acid (dsRNA) viruses.
| Virus Family | dsRNA Features | Capsid Features | ||||
|---|---|---|---|---|---|---|
| Nº Segments | Size (kbp) | MW c (MDa) | CP (residue) | Φ d/ir e (nm) | dsRNA Density (bp/100 nm3) f | |
| HSV a | 1 | ~152 | 103.7 | 1374 | ~130/43 | 46 |
| Reoviridae | ||||||
| Orthoreovirus | 10 | ~23.5 | 16 | 1275 | ~60/24.5 | 38 |
| Rotavirus | 11 | ~18.5 | 12.6 | 880 | ~52/23.5 | 34 |
| Orbivirus, BTV | 10 | ~19.2 | 13.1 | 901 | ~52/22 | 43 |
| Aquareovirus, GCRV | 11 | ~23.6 | 16 | 1027 | ~60/23 | 46 |
| Phytoreovirus, RDV | 12 | ~25.7 | 17.5 | 1019 | ~57/26 | 35 |
| Cypovirus, CPV | 10 | ~31.4 | 21.4 | 1333 | ~58/24 | 54 |
| Mycoreovirus, MyRV1 | 11 | 23.4 | 16 | |||
| Picobirnaviridae | 2 | ~4.2 | 2.9 | 590 | ~35/14 | |
| Cystoviridae, phage ϕ6 | 3 | ~13.4 | 9.1 | 769 | ~50/20 | 40 |
| Totiviridae, ScV-L-A | 1 | ~4.6 | 3.1 | 680 | ~43/17 | 22 |
| Partitiviridae, PsV-S | 1 (2) b | ~1.7 (3.3) | 1.2 (2.2) | 420 | ~35/12 | 23 |
| Chrysoviridae, PcV | 1 (4) b | ~3.2 (12.6) | 2.2 (8.6) | 109 | ~40/16 | 19 |
| Megabirnaviridae, RnMBV1 | 1 (2) b | ~8.1 (16.2) | 5.5 (11) | 135 | ~52/19 | 28 |
| Quadriviridae, RnQV1 | 1–2 (4) | ~4.3 (17.1) | 2.9 (11.7) | 1356 + 1061 | ~47/16 | 25 (50) g |
a Herpes simplex virus, a dsDNA virus with liquid-crystalline packing of the encapsidated, B-form dsDNA. b For PsV-S, PcV, and RnMBV1 dsRNA, the genome is formed by two, four, or two dsRNA molecules, respectively, but a mean value was calculated for one dsRNA molecule/particle in each column. c Molecular weights (MW) were calculated assuming a mass of 682 Da/bp. HSV dsDNA is assumed to have a B-form. d Outer diameter. e Inner radius. f Densities when volume of a perfect sphere is assumed and any other internal components are ignored. g 25 if there is one dsRNA molecule/particle; 50 if there are two dsRNA molecules/particle.