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. 2018 Aug 28;6(3):90. doi: 10.3390/biomedicines6030090

Table 3.

In vitro lumen to hemolymph flux of Hv1a and analogs across the midgut of Manduca sexta larvae when present at different concentrations in the luminal fluid. Data are mean ± S.E.M, n = 9–19.

Concentration of Hv1a or Analog (µM) Lumen to Hemolymph Flux (pmol/cm2/h)
Hv1a Cyclic Hv1a 1,4-SeSe-Hv1a
0.1 11.8 ± 2.7 0.14 ± 0.03
1.0 41 ± 11 1.7 ± 0.6
10 351 ± 32 94 ± 16
10 287 ± 23 227 ± 14