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(a) 2D interaction diagrams for the binding of tubulin (PDB code: 1SAO) with colchicine; (b) the structure of (E)-1-(5-Bromo-2-(4-fluorophenyl)benzofuran-7-yl)-3-(4-methoxyphenyl)prop-2-en-1-one (3i); (c) the structure of (E)-1-(5-Bromo-2-(3-fluorophenyl)benzofuran-7-yl)-3-(4-(trifluoromethoxy)phenyl)prop-2-en-1-one (3o). Residues are annotated with their three-letter amino acid code.
