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Compounds 3a–y and their substitution pattern.
| R1 | Substitution Pattern of Compounds 2a–e & 3a–y | |||||
|---|---|---|---|---|---|---|
| 2 | 3a–e (R2) | 3f–j (R2) | 3k–o (R2) | 3p–t (R2) | 3u–y (R2) | |
| 4-H | 2a | 3a (H) | 3f (4-F) | 3k (3-F) | 3p (3-Cl) | 3u (4-OMe) |
| 4-F | 2b | 3b (H) | 3g (4-F) | 3l (3-F) | 3q (3-Cl) | 3v (4-OMe) |
| 4-Cl | 2c | 3c (H) | 3h (4-F) | 3m (3-F) | 3r (3-Cl) | 3w (4-OMe) |
| 4-OMe | 2d | 3d (H) | 3i (4-F) | 3n (3-F) | 3s (3-Cl) | 3x (4-OMe) |
| 4-OCF3 | 2e | 3e (H) | 3j (4-F) | 3o (3-F) | 3t (3-Cl) | 3y (4-OMe) |
