Table 2.
Cytotoxic effects of 3a–y against MCF-7 cell line. The results are presented as IC50 (μM) ± standard deviation (SD) from three individual experiments.
| Compounds | MCF-7 Cell Line IC50 (μM) ± SD |
|---|---|
| 3a | 47.96 ± 2.10 |
| 3b | 0.55 ± 0.24 |
| 3c | >100 |
| 3d | 22.78 ± 0.86 |
| 3e | 0.59 ± 0.21 |
| 3f | 35.81 ± 1.20 |
| 3g | 48.59 ± 2.10 |
| 3h | 54.16 ± 0.40 |
| 3i | 3.55 × 10−4 ± 0.07 |
| 3j | 16.00 ± 0.62 |
| 3k | 23.01 ± 0.38 |
| 3l | >100 |
| 3m | 14.75 ± 0.33 |
| 3n | 39.25 ± 0.42 |
| 3o | 7.87 ± 0.25 |
| 3p | 12.63 ± 0.23 |
| 3q | 23.82 ± 0.29 |
| 3r | 66.75 ± 0.84 |
| 3s | 2.69 ± 0.23 |
| 3t | 26.62 ± 0.27 |
| 3u | 48.96 ± 0.30 |
| 3v | 28.43 ± 0.46 |
| 3w | 30.62 ± 0.35 |
| 3x | 69.09 ± 0.76 |
| 3y | 43.17 ± 0.28 |
| Actinomycin D | 37.82 ± 1.30 |