Figure 2.

Effect of DMY on blood pressure in mice after transverse aortic constriction (TAC). Male C57BL/6 mice were given DMY (250 mg/kg/day) or carboxymethylcellulose (CMC) (0.5%) by gavage for 2 weeks followed by TAC or sham operation. Then DMY was administered for another 2 weeks. (A) Systolic blood pressure (SBP) was measured by tail-cuff method weekly; (B) SBP, diastolic blood pressure (DBP) and average mean artery pressure (MAP) were measured via carotid artery cannulation 2 weeks after TAC. ** p < 0.01 versus Sham (n = 8).