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. 2018 Aug 22;10(9):1139. doi: 10.3390/nu10091139

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of MPE (12.5, 25, 50 μg/mL) on production of nitric oxide in BV-2 microglia and resulting influence in non-contact co-culture in SH-SY5Y neuroblastoma. Effects on levels of nitric oxide produced in BV-2 induced with lipopolysaccharide (LPS) (A), and on SH-SY5Y cell viability after co-culture with BV-2 LPS-induced media (B). All data expressed as mean ± standard error (n = 3), significance was reported by ANOVA followed with Dunnett multiple comparison testing, as compared with control p ≤ 0.0001 (####); as compared with toxic agent, p ≤ 0.01 (**), p ≤ 0.001 (***), and p ≤ 0.0001 (****).