Table 1.
Relative abundance of butyrate-producing bacteria.
| Relative Abundance (%) | Genus | |||||||
|---|---|---|---|---|---|---|---|---|
| Roseburia (×10−2) | Butyricimonas (×10−2) | Coprococcus (×10−2) | Clostridium (×10−2) | Ruminococcus | Eubacterium | Total | ||
| D48 | WT | 5.5 ± 1.12 | 1.9 ± 0.35 | 0.5 ± 0.14 | 0 | 0.83 ± 0.13 | 0.54 ± 0.27 | 1.45 ± 0.031 |
| KO | 85.3 ± 19.80 | 5.3 ± 1.33 | 8.8 ± 0.97 | 30.3 ± 0.22 | 3.23 ± 0.57 | 2.97 ± 1.17 | 7.50 ± 1.39 * | |
| D98 | WT | 50.4 ± 9.79 | 0.5 ± 0.08 | 6.7 ± 0.91 | 0 | 0.090 ± 0.031 | 0.14 ± 0.092 | 0.77 ± 0.15 |
| KO | 216.8 ± 3.72 | 9.8 ± 2.22 | 43 ± 3.59 | 52.8 ± 1.51 | 3.30 ± 0.98 | 4.12 ± 1.34 | 10.65 ± 1.36 * | |
| D118 | WT | 38.1 ± 7.33 | 0 | 4.1 ± 0.72 | 0 | 0.01 ± 0.008 | 0.14 ± 0.014 | 0.57 ± 0.14 |
| KO | 58.3 ± 12.08 | 7.9 ± 1.71 | 13 ± 3.34 | 3.8 ± 0.79 | 3.06 ± 0.82 | 3.70 ± 0.67 | 7.58 ± 1.28 * | |
| D138 | WT | 202.9 ± 30.85 | 0 | 6.7 ± 1.47 | 0 | 0.02 ± 0.0056 | 0.08 ± 0.04 | 2.93 ± 0.44 |
| KO | 24.2 ± 3.91 | 4.5 ± 0.88 | 12 ± 2.58 | 1.9 ± 0.19 | 3.30 ± 0.74 | 1.12 ± 0.47 | 4.85 ± 0.97 * | |
| D178 | WT | 33.3 ± 2.82 | 0 | 4.0 ± 0.81 | 0 | 0.02 ± 0.0069 | 0.17 ± 0.07 | 0.55 ± 0.058 |
| KO | 51.2 ± 11.40 | 4.1 ± 0.76 | 7.2 ± 0.2 | 0.9 ± 0.00 | 5.89 ± 0.93 | 1.52 ± 0.81 | 8.04 ± 1.34 * | |
Note: D48 indicated that the samples were collected at Day 48, and so on. WT, Muc2+/+, KO, Muc2−/−. * p < 0.05, comparison between Muc2−/− and Muc2+/+ mice.