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. 2018 Sep 1;19(9):2601. doi: 10.3390/ijms19092601

Figure 10.

Figure 10

Schematic representation of the proposed mechanism by which GN protects against alcoholic liver disease (ALD) by inhibiting hepatic steatosis, oxidative stress, and inflammation. GN exerts potential hepatoprotective effects against ethanol-induced liver injury by activating SIRT1/AMPK and inhibiting CYP2E1. ↑ means upregulation and ↓ means downregulation