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. 2018 Sep 6;19(9):2637. doi: 10.3390/ijms19092637

Figure 2.

Figure 2

Histopathological sections of the mammary tissues (H&E, 100× and 400×). The mammary tissues (n = 6 in each group) from each group were processed for histological evaluation. Representative histological changes in the mammary tissues from each group were as follows: (A,F) no-treatment (NT) group; (B,G) lipopolysaccharide (LPS) group; (C,H) LPS + 1 mg/kg peiminine group; (D,I) LPS + 3 mg/kg peiminine group; and (E,J) LPS + 5 mg/kg peiminine group. Histologic grade of the mammary gland (K). The histological morphology and pathology results showed that peiminine treatment alleviated the LPS-induced pathological changes. The number sign (#) indicates a significant difference from the NT group at p < 0.0001. The tetrad asterisks (****) indicate p < 0.0001 and the double asterisks (**) indicate p < 0.01 vs. the LPS group.