Table 2.
Biomechanical Testing Indices.
| Donor Bone | Scaffold | ||
|---|---|---|---|
| FEA Modeling | |||
| Yield Stress (von Mises) | 11,372 ± 286 MPa | 10,922 ± 327 MPa | p = 0.39 |
| Stiffness | 31,921± 8250 N/mm | 18,840 ± 6603 N/mm | p = 0.26 |
| Failure Load | 148.0 ± 35.7 MPa | 89.5 ± 29.5 MPa | p = 0.25 |
| Mechanical Testing | |||
| Young’s Modulus | 236.6 ± 11.8 MPa | 114.2 ± 17.8 MPa | p < 0.01 |
| Stiffness | 1544.0 ± 76.2 N/mm | 727.6 ± 120.1 N/mm | p < 0.01 |
| Failure Load | 14.5 ± 1.8 MPa | 13.6 ± 1.8 MPa | p = 0.72 |
| Strain at Failure | 0.088 ± 0.006 | 0.230 ± 0.014 | p < 0.01 |
Biomechanical properties of representative unprocessed bone and decellularized scaffolds are presented as the mean ± standard error and compared by independent samples t-tests. Parameters were measured by finite element analysis (FEA) modeling as well as mechanical compression testing on an Instron® MTS.