Table 1.
Patient characteristics of pancreatic neuroendocrine tumors (pNET).
| Parameters | Cases | p Value a |
|---|---|---|
| Gender, n (%) | ||
| Male | 32 (56.1%) | 0.354 |
| Female | 25 (43.9%) | |
| Age (mean ± SD) | 60.9 ± 14.4 | n.a. |
| Size (mean (cm) ± SD) | 2.69 ± 2.34 | n.a. |
| Localization, n (%) b | ||
| Head | 25 (44.6) | 0.067 |
| Corpus | 11 (19.6) | |
| Cauda | 20 (35.7) | |
| TNM, n c | ||
| T1/2/3/4 | 24/13/17/3 | ** 0.001 |
| N0/1 | 38/19 | * 0.012 |
| M0/1 | 46/11 | ** 0.000 |
| Grading, n (%) | ||
| G1 | 32 (56.1) | n.a. |
| G2 | 17 (29.8) | |
| G3 | 8 (14.0) | |
| R status, n (%) | ||
| R0 | 51 (89.5) | ** 0.000 |
| R1 | 5 (8.8) | |
| R2 | 1 (1.8) | |
| OS, n (%) | ||
| Yes | 47 (82.5) | ** 0.000 |
| No | 10 (17.5) | |
| DFS, n (%) | ||
| Yes | 34 (73.9) | ** 0.001 |
| No | 12 (26.1) | |
| Proliferation/Mitosis | ||
| H&E d | 12.8 ± 27.1 | n.a. |
| pHH3 e | 15.0 ± 31.4 | |
| Ki-67 (%) f | 10.8 ± 21.3 | |
| Hormone activity n (%) g | ||
| No | 30 (52.6) | 0.691 |
| Yes | 27 (47.4) | |
a χ2 test; b Reduced case numbers due to unknown data; c according to current TNM (7th edition (2010)); d H&E-associated mitotic activity per 10 high power fields; e pHH3-associated mitotic activity per 10 high power fields; f Ki-67-associated proliferation index (% per 2000 tumor cells); g measured by immunohistochemistry; n.a., not applicable; SD, standard deviation.