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. 2018 Sep 18;19(9):2814. doi: 10.3390/ijms19092814

Table 3.

Number of differentially expressed transcripts in comparisons of the experiment groups of the 19th DLR parabolic flight campaign. Differential expression is defined as t-test p-value < 0.05; fold change (FC) ≤ −1.3 or ≥ +1.3. If the ratio is <1, FC is calculated as the negative reciprocal of the ratio. The term “transcripts” refers to 188 oxidative stress-related transcripts, representing 86 genes. For the abbreviations of the experiment group names see Table 1.

Hypergravity-Sensitive Transcripts
Differentially expressed in BL-PFC hyp-g vs. H/W 1g GC (TEXUS-49-analogous) Average FC of BL-PFC hyp-g vs. H/W 1g GC Min/Max FC of BL-PFC hyp-g vs. H/W 1g GC
Differentially Expressed Transcripts up-regulated 23 2.088 3.042
down-regulated 20 −1.770 −2.505
total number 43
Hypergravity-Sensitive Transcripts, 1g IF-Controlled
Differentially expressed in BL-PFC hyp-g vs. 1g IF, but not differentially expressed in 1g IF vs. H/W 1g GC Average FC of BL-PFC hyp-g vs. 1g IF Min/Max FC of BL-PFC hyp-g vs. 1g IF
Differentially Expressed Transcripts up-regulated 19 1.727 2.184
down-regulated 16 −1.590 −2.014
total number 35
Microgravity-Sensitive Transcripts, BL-Controlled
Differentially expressed in µg vs. BL-PFC hyp-g, but not differentially expressed in the same direction in BL-PFC hyp-g vs. H/W 1g GC (TEXUS-49-analogous) Average FC of µg vs. BL-PFC hyp-g Min/Max FC of µg vs. BL-PFC hyp-g
Differentially expressed transcripts up-regulated 2 1.347 1.356
down-regulated 1 −1.495 −1.495
total number 3
Microgravity-Sensitive Transcripts, BL and 1g IF-Controlled
Differentially expressed in µg vs. BL-PFC hyp-g, but not differentially expressed in 1g IF vs. H/W 1g GC or in the same direction in BL-PFC hyp-g vs. 1g IF Average FC µg vs. BL-PFC hyp-g Min/Max µg vs. BL-PFC hyp-g
Differentially expressed transcripts up-regulated 1 1.338 1.338
down-regulated 1 −1.495 −1.495
total number 2