Table 3.
Associations of combined Tg and HDL-C status according to different combinations of high/low categories of these two lipids among those with T2DM (n = 181) and prediabetes (n = 197).
| N (%) | Unadjusted | Adjusted | ||||
|---|---|---|---|---|---|---|
| T2DM | Cases | Events | OR (95% CI) | p Value | OR (95% CI) | p Value |
| Normal Tg and Normal HDL-C | 140 (6.1) | 2 (1.4) | Reference | Reference | ||
| High Tg and Normal HDL-C | 40 (1.7) | 6 (15.0) | 12.56 (2.42, 65.15) | 0.003 | 10.47 (1.99, 55.17) | 0.006 |
| Normal Tg and Low HDL-C | 1455 (63.5) | 64 (4.4) | 3.35 (0.81, 13.82) | 0.095 | 3.31 (0.80, 13.74) | 0.099 |
| High Tg and Low HDL-C | 658 (28.7) | 109 (16.6) | 15.60 (3.80, 64.02) | <0.001 | 12.75 (3.08, 52.65) | <0.001 |
| Prediabetes | ||||||
| Normal Tg and Normal HDL-C | 140 (6.1) | 4 (2.9) | Reference | Reference | ||
| High Tg and Normal HDL-C | 40 (1.7) | 2 (5.0) | 2.09 (0.37, 11.94) | 0.405 | 1.95 (0.34, 11.20) | 0.453 |
| Normal Tg and Low HDL-C | 1455 (63.5) | 110 (7.6) | 2.88 (1.04, 7.92) | 0.041 | 2.81 (1.02, 7.77) | 0.046 |
| High Tg and Low HDL-C | 658 (28.7) | 81 (12.3) | 5.80 (2.09, 16.11) | 0.001 | 4.89 (1.75, 13.68) | 0.002 |
Adjusted for age, hypertension, and central obesity. Variables were categorized as follows: Tg (normal < 1.7 vs. high ≥ 1.7 mmol/L); HDL-C (normal M ≥ 1.04 & F ≥ 1.3 vs. low M < 1.04 and F < 1.3 mmol/L). Abbreviation: T2DM, type 2 diabetes mellitus; CI, confidence interval; Tg, triglycerides; HDL-C, high-density lipoprotein.