Figure 6.

Structural stability of tissue-engineered skin substitutes matured in vitro for various time at the air–liquid interface before measuring surface area after an additional 48 h on agar substrate. Resulting contraction indicated as a percentage of the initial (at t = 0 h on agar) surface area of TES FS1-5× 10d A/L (triangles), FS1-10× (squares), and FS3-1× (circles) cultured for 4 (4 A/L), 10 (10 A/L), and 17 (17 A/L) days at the air–liquid interface remaining after 48 h of in vitro testing on agar.