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. 2018 Sep 1;10(9):1194. doi: 10.3390/nu10091194

Table 1.

Overview of animal studies on sex-specificity in maternal milk.

Species Sample Size Offspring Age at Collection Sex-Specific Difference Study
Primates Rhesus Macaque (Macaca mulatta) 106 3–4 months ↑ energy and ↑ fat for males Hinde, 2007 [43]
114 (62 F, 52 M) ↓ volume ↑ energy density for males Hinde, 2009 [42]
104 (61 F, 43 M) ↑ calcium for females Hinde et al., 2013 [41]
Ruminants Holstein breed of cow (Bos Taurus) 113,750 (data from lactation records) not reported ↑ volume for females Hinde et al., 2014 [44]
Red deer (Cervus elaphus hispanicus) 91 (44 M, 47 F) 2, 6, 10 and 14 weeks ↑ volume, ↑ protein, ↑ fat and ↑ lactose for males Landete-Catillejos et al., 2005 [47]
Marsupials Kangaroo (Macropus giganteus) 91 6–10 months ↑ protein for males Quesnel et al., 2017 [45]
Wallaby (Macropus eugenii) 2 milking sessions: 15 in July (6 M, 9 F), 11 in October (4 M, 7 F) 4–8 months ↑ protein for males Robert and Braun, 2012 [46]

F, female offspring; M, male offspring; ↑, higher compared to the opposite sex; ↓, lower compared to the opposite sex.