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Effect of HE-02 (6.25, 12.5 or 50 mg/kg) on (A) Tumoral volume and (B) Cell viability. Data presented as mean ± standard error of mean (SEM) of six animals analyzed by analysis of variance (ANOVA) followed by Tukey test. a p < 0.05 compared to tumor control group, b p < 0.05 compared to 6.25 mg/kg dose. c p < 0.05 compared to all HE-02 doses.
