Histopathology of the kidneys of different groups: (A) Control, cortical region, renal glomerulus (arrow) and cortical labyrinth (star). (B) Control, medullary region, collecting tubules (star), loop of Henle and vessels straight (arrow). (C) Group 5-FU, cortical region, glomerulus (arrow) and cortical labyrinth (star). (D) Group HE-02 (12.5 mg/kg), subcapsular region, cell infiltrate (arrow). (E) Group HE-02 (12.5 mg/kg), cortical region, renal corpuscle (arrow) and cortical labyrinth (star). (F) Group HE-02 (12.5 mg/kg), medullary region, loop of Henle and medullar rays (arrow), collecting tubules (star). A, B, C, D, E and F-HE, A.T. ×400.