Table 3.
Group | Dose (mg/kg) | AST (U/L) | ALT (U/L) | Urea (mg/dL) | Creatinine |
---|---|---|---|---|---|
Control | 181.80 ± 25.28 | 25.33 ± 3.84 | 36.83 ± 3.46 | 0.24 ± 0.1 | |
HE-02 | 12.5 | 247.80 ± 45.19 | 21.75 ± 2.32 | 55.00 ± 5.30 a | 0.31 ± 0.03 |
5-FU | 25 | 155.20 ± 20.78 | 22.33 ± 4.55 | 37.80 ± 1.71 | 0.26 ± 0.01 |
Data presented as mean ± SEM analyzed by ANOVA followed by Tukey test. a p < 0.05 compared to tumor control group.