Table 5.
SFA, MUFA and PUFA in the brains of Wt and 5xFAD control and FO supplemented mice.
| FA (%) | Wt | Wt FO | 5xFAD | 5xFAD FO |
|---|---|---|---|---|
| Palmitic acid (16:0) | 28.49 ± 1.46 | 25.83 ± 2.57 a | 27.00 ± 1.85 | 29.11 ± 3.17 |
| Stearic acid (18:0) | 25.92 ± 3.0 | 22.94 ± 0.99 | 24.29 ± 2.20 | 26.89 ± 2.53 |
| SFA | 54.41 ± 22.69 | 48.77 ± 4.36 a1 | 51.29 ± 1.64 a | 56.01 ± 4.36 b |
| Palmitoleic acid (16:1n-7) | 0.46 ± 0.15 | 0.49 ± 0.13 | 0.37 ± 0.09 | 0.47 ± 0.10 |
| Oleic acid (18:1n-9) | 14.32 ± 1.52 | 15.02 ± 0.75 | 14.64 ± 1.67 | 14.05 ± 2.38 |
| Vaccenic acid (18:1n-7) | 3.85 ± 0.26 | 4.71 ± 0.54 a | 4.19 ± 0.77 | 3.93 ± 0.61 |
| MUFA | 18.62 ± 1.87 | 20.40 ± 0.31 a | 19.21 ± 2.33 | 18.45 ± 2.86 |
| n-6 | 11.60 ± 0.49 | 12.66 ± 0.99 a | 13.62 ± 0.85 a2 | 10.51 ± 0.66 a1,b2 |
| n-3 | 15.26 ± 0.71 | 18.17 ± 1.84 a1 | 15.88 ± 1.72 | 15.03 ± 1.56 |
| PUFA | 26.97 ± 1.06 | 30.83 ± 2.75 a1 | 29.50 ± 2.46 a | 25.54 ± 2.16 b |
SFA, saturated fatty acids; MUFA, mono-unsaturated fatty acids; n-6, omega-6 polyunsaturated fatty acids (PUFA); n-3, omega-3 polyunsaturated fatty acids. Values are presented as mean ± SD. Significantly different from Wt group: a p < 0.05, a1 p < 0.01, a2 p < 0.001. Significantly different from 5xFAD group: b p < 0.05, b2 p < 0.001.