Table 1.

Computed binding energy values (ΔG_binding, k_cal/mol) for the molecular docking analysis of the best binding poses between ethyl gallate (partially-ionized vs non-ionized) and cyclooxygenase 1 and 2 (COX-1 and COX-2) proteins.

Type of Protein	Binding Energy Value ΔGbinding (kcal/mol)
	No ionization	C-4-OH ionization	C-3-OH ionization
COX-1 protein	−3.652	−94.444	−108.779
COX-2 protein	−6.398	−100.929	−132.742