Table 2.
Effect of LV, HS, and the MetA-mixed extract of LV and HS on biochemistry parameters in serum and liver tissue of HFD-induced obese mice.
| NFD | HFD | HFD | |||||
|---|---|---|---|---|---|---|---|
| GC_245 | LV_100 | HS_100 | MetA_50 | MetA_100 | |||
| TG (mg/dL) | 91.5 ± 4.1 a | 121.9 ± 10.5 | 106.6 ± 6.0 ab | 75.7 ± 4.5 ac | 100.4 ± 3.0 ab | 109.4 ± 8.0 ab | 105.4 ± 2.5 ab |
| NEFA (mEq/L) | 3.0 ± 0.1 a | 3.3 ± 0.2 a | 2.8 ± 0.1 a | 2.5 ± 0.1 b | 2.6 ± 0.1 b | 3.3 ± 0.17 a | 2.6 ± 0.1 b |
| T-CHO (mg/dL) | 118.4 ± 2.4 a | 317.1 ± 28.3 b | 186.8 ± 10.4 | 262.8 ± 36.2 b | 321.4 ± 34.4 b | 282.2 ± 15.7 b | 149.7 ± 6.3 |
| LDL-CHO (mg/dL) | 10.1 ± 0.5 a | 16.7 ± 1.5 b | 8.9 ± 0.8 ac | 13.2 ± 1.7 ab | 13.3 ± 1.4 ab | 11.3 ± 0.6 | 10.5 ± 0.6 ac |
| HDL-CHO (mg/dL) | 48.4 ± 1.1 a | 52.9 ± 2.2 a | 54.6 ± 2.6 a | 59.3 ± 3.4 a | 60.1 ± 2.6 b | 72.0 ± 3.6 c | 59.3 ± 2.5 a |
| ALT (mg/dL) | 20.7 ± 0.7 a | 61.6 ± 12.4 b | 24.8 ± 2.2 a | 21.4 ± 1.3 | 35.8 ± 5.7 a | 37.5 ± 8.3 a | 29.2 ± 4.1 a |
| AST (mg/dL) | 81.1 ± 8.6 | 118.0 ± 35.1 | 77.9 ± 9.6 | 91.4 ± 16.3 | 80.0 ± 7.1 | 82.1 ± 5.0 | 81.1 ± 5.8 |
| Creatinine (mg/dL) | 0.29 ± 0.01 | 0.34 ± 0.01 | 0.35 ± 0.01 | 0.33 ± 0.02 | 0.29 ± 0.01 | 0.34 ± 0.02 | 0.35 ± 0.01 |
TG, Triglycerides; NEFA, nonesterified fatty acid; T-CHO, Total cholesterol; HDL-CHO, high-density lipoprotein-CHO; LDL-CHO, low-density lipoprotein-CHO; AST, aspartate aminotransferase; ALT, alanine aminotransferase; HFD, 60% high-fat-diet control group; HFD + GC_245, HFD contains Garcinia cambogia extract (245 mg/kg)-fed group; HFD + LV_100, HFD contains lemon verbena extract (100 mg/kg)-fed group; HFD + HS_100, HFD contains Hibiscus flower extract (100 mg/kg)-fed group; HFD + MetA_50, HFD contains the MetA-mixed extract of lemon verbena plus Hibiscus flower (50 mg/kg)-fed group; HFD + MetA_100, HFD contains the MetA-mixed extract of lemon verbena plus Hibiscus flower (100 mg/kg)-fed group. Values are expressed as means ± SEM (n = 10). a–c Values within arrow with different letters are significantly different from each other at p < 0.05 as determined by Turkey’s multiple-range test.