Table 5.
Gene symbol, gene title, and relative fold change for the genes that showed an over or down expression value higher than 1.5 (p < 0.05) in the rat livers 1.
| Symbol | Gene Name | NL–NA | HA–NA | HL–NA | HL–HA |
|---|---|---|---|---|---|
| Fatty acid β-oxidation | |||||
| Cpt2 | Carnitine palmitoyltransferase 2 | - | 4.51 | - | - |
| Cpt1a | Carnitine palmitoyltransferase 1a, liver | - | 2.52 | - | - |
| Acox1 | Acyl-coenzyme A oxidase 1, palmitoyl | 1.90 | - | - | - |
| Cholesterol transport and metabolism | |||||
| Abca1 | ATP-binding cassette, subfamily A (ABC1), member 1 | - | 2.39 | - | - |
| Hmgcr | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | - | 1.52 | - | - |
| Cd36 | CD36 molecule (thrombospondin receptor) | 5.84 | −3.28 | 4.23 | - |
| Pparg | Peroxisome proliferator-activated receptor gamma | - | 1.64 | - | - |
| Abcg1 | ATP-binding cassette, subfamily G, member 1 | - | 2.43 | - | - |
| Cyp7a1 | Cytochrome P450, family 7, subfamily a, polypeptide 1 | 1.52 | 1.51 | - | - |
| Lepr | Leptin receptor | - | 2.43 | - | - |
| Nr1h2 | Nuclear receptor subfamily 1, group H, member 2 | 1.66 | −1.68 | - | - |
| Nr1h4 | Nuclear receptor subfamily 1, group H, member 4 | - | - | - | 1.80 |
| Srebf2 | Sterol regulatory element binding transcription factor 2 | 2.27 | - | - | - |
| Apob | Apolipoprotein B | −6.43 | 6.80 | −4.66 | - |
| Other lipid transport and metabolism | |||||
| Scd1 | Stearoyl-coenzyme A desaturase 1 | 2.09 | - | - | - |
| Lpl | Lipoprotein lipase | −4.05 | 6.22 | −3.33 | - |
| Acsl5 | Acyl-coa synthetase long-chain family member 5 | −1.64 | 1.90 | - | - |
| Dgat2 | Diacylglycerol O-acyltransferase homolog 2 (mouse) | - | 1.51 | - | - |
| Ppa1 | Pyrophosphatase (inorganic) 1 | - | −2.20 | 3.57 | - |
| Fabp5 | Fatty acid binding protein 5, epidermal | - | - | 2.99 | - |
| Hnf4a | Hepatocyte nuclear factor 4, alpha | - | - | 1.76 | 1.79 |
| IL10 | Interleukin 10 | 2.83 | - | - | - |
1 The fold change for each gene in groups HA, HL, and NL was calculated taking as reference a value of 1 for the group NA. For comparison, HA vs. HL reference values of 1 have been given to group HA.