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. 2018 Jul 11;8(3):49. doi: 10.3390/biom8030049

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Soraphen A resistance and lipolysis defect in deg1 mutants. (A) Microtiter based measurement of growth inhibition of indicated strains by soraphen A. Relative growth refers to optical density (O.D 600 nm) of microcultures with indicated concentrations of soraphen A as compared to soraphen A free cultures. Measurements were carried out in triplicate and shown as mean plus standard deviation. (B) Lipid droplet dynamics and (C) growth of BY4741 (WT) and its isogenic elp3 and deg1 mutants was determined during exponential phase of growth (6 h). The mean ± S.D. of three independent experiments is shown.