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. 2018 Sep 1;10(9):1197. doi: 10.3390/nu10091197

Table 2.

Association between plasma 25-hydroxy vitamin D and the age-adjusted standard score (Raven’s Standard Progressive Matrices test) before and after adjusting for potential confounders.

Vitamin D Status Model 1 Model 2 Model 3 Model 4 Model 5
β [95%CI] β [95%CI] β [95%CI] β [95%CI] β [95%CI]
25-OH-D levels nmol/L 0.03 0.01 0.00 0.00 −0.01
[−0.02, 0.08] [−0.04, 0.07] [−0.05, 0.06] [−0.05, 0.06] [−0.07, 0.05]
p-value 0.23 0.70 0.95 0.85 0.73
Q1 (25-OH-D < 19.2 nmol/L) (n = 337) [Reference] [Reference] [Reference] [Reference] [Reference]
Q2 (25-OH-D ≥ 19.2 to <29.7 nmol/L) (n = 346) 0.86 1.12 −0.39 1.15 0.82
[−2.65, 4.38] [−2.32, 4.58] [−4.28, 3.49] [−2.29, 4.59] [−2.82, 4.46]
Q3 (25-OH-D from 29.7 to <44.1 nmol/L) (n = 344) 2.67 2.29 −0.26 2.69 0.84
[−0.86, 6.19] [−1.43, 6.02] [−6.25−5.72] [−1.03, 6.41] [−3.24, 4.92]
Q4 (25-OH-D ≥ 44.1 nmol/L) (n = 343) 2.91 0.95 −0.70 0.50 −0.42
[−0.62, 6.43] [−3.00, 4.90] [−7.92, 6.53] [−3.47, 4.47] [−4.82, 4.01]
p-value 0.30 0.67 1.00 0.45 0.88
Severe deficiency (25-OH-D < 25 nmol/L) (n = 544) [Reference] [Reference] [Reference] [Reference] [Reference]
Deficiency (25-OH-D ≥ 25 to <50 nmol/L) (n = 572) 2.28 2.52 2.70 2.71 1.36
[−0.46, 5.04] [−0.39, 5.44] [0.22, 5.63] [−0.22, 5.63] [−1.86, 4.59]
Insufficiency (25-OH-D ≥ 50 to <75 nmol/L) (n = 205) 1.40 −0.66 −0.93 −0.94 −1.53
[−2.36, 5.16] [−4.66, 3.34] [−4.94, 3.09] [−4.97, 3.08] [−6.01, 2.94]
Sufficiency (25-OH-D ≥ 75 nmol/L) (n = 49) 5.46 4.98 2.79 3.02 1.47
[−1.39, 12.31] [−1.96, 11.92] [−4.16, 9.74] [−3.93, 9.98] [−5.96, 8.91]
p-value 0.24 0.11 0.11 0.10 0.48

Q1 to Q4: quartile one to quartile four; Model 1: unadjusted; Model 2: adjusted for socio-demographic factors (gender, nationality, governorate, education of the father, education of the mother, type of housing, season of birth, and passive smoking at home); Model 3: adjusted for variables in Model 2 in addition to grade level, sleeping hours during weekends, having nap during weekend, time spent outside during the last 3 months during weekdays and weekends, reporting medical condition, and frequency of consumption of sugary drinks; Model 4: adjusted for variables in Model 3 in addition to BMI categories; Model 5: adjusted for variables in Model 4 in addition to parathyroid hormone, vitamin B12, and transferrin saturation all as quartiles.