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. 2018 Aug 24;19(9):2499. doi: 10.3390/ijms19092499

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Mechanisms for BMPR2 deficiency. ALK = activin-like receptor; BMP = bone morphogenetic protein; BMPR2 = bone morphogenetic protein receptor 2; CAV1 = caveolin 1; gp-120 = envelope glycoprotein GP120; HIV = human immunodeficiency virus; Nef = negative factor; RAGE = receptor for advanced glycation end products; SMAD = mothers against decapentaplegic; SMURF = SMAD-specific E3 ubiquitin protein ligase; Tat = trans-activator of transcription; VEGFR3 = Vascular endothelial growth factor receptor 3.