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. Author manuscript; available in PMC: 2019 Sep 30.
Published in final edited form as: Wiley Interdiscip Rev Syst Biol Med. 2018 Mar 30;10(5):e1422. doi: 10.1002/wsbm.1422

FIGURE 2.

FIGURE 2

Wnt receptors. Several cell surface proteins directly bind Wnt proteins, including Frizzled (FZD), LRP5 & 6 (fly homolog is Arrow), PTK7 (fly homolog is Otk), ROR1 & 2, and RYK (fly homolog is Drl). Abbreviations: aa = amino acids, CRD = cysteine-rich domain, C = carboxy terminus, Ig = immunoglobulin domain, N = amino terminus, WIF = Wnt inhibitory factor