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Restriction on caspase-3 activation in vitro.
Notes: MDCK cells infected with H1N1 virus were untreated (Mock) or treated with RBV, SeNPs, and Se@RBV for 48 hours. Cells without infection and treatment were performed as control. Caspase-3 activity was checked and expressions of proteins related to caspase-3 activation were detected. *P<0.05 and **P<0.01.
Abbreviations: MDCK, Madin-Darby Canine Kidney; RBV, ribavirin; SeNPs, selenium nanoparticles; Se@RBV, SeNPs loaded with RBV.
