Table S1.

Influence of tumor location on the associations of different MSI/BRAF mutation genotypes with OS in colorectal cancer analyzed by meta-analysis regression

Comparison	Meta-analysis regression
	Coef	Z	P-value
MSImut/MSSmut	−2.712615	−1.410	1.585E-01
MSIwt/MSSwt	−4.083789	−1.320	1.868E-01
MSImut/MSIwt	0.0270588	0.030	9.761E-01
MSSmut/MSSwt	0.9104029	0.950	3.421E-01

Note: The difference in tumor location in individual included studies was reflected by the ratio of proximal or right colon cancer to the total colorectal cancers and used as the covariate in meta-analysis regression.

Abbreviations: Coef, coefficient; MSImut, microsatellite instability and BRAF mutation; MSIwt, microsatellite instability and BRAF wild type; MSSmut, microsatellite stable and BRAF mutation; MSSwt, microsatellite stable and BRAF wild type; OS, overall survival.