Table 2.
Cox regression analysis of mortality risk for all patients
| Variable | Univariate analysis (n =70)
|
Multivariate analysis (n =70)
|
||||
|---|---|---|---|---|---|---|
| HR | P-value | 95% CI | aHR | P-value | 95% CI | |
| Group | ||||||
| Group A (Ref.) | 1.00 | – | – | 1.00 | – | – |
| Group B | 2.94 | 0.009 | (1.32–6.57) | 3.73 | 0.011 | (1.36–10.25) |
| Group C | 1.17 | 0.737 | (0.47–2.91) | 1.67 | 0.356 | (0.57–4.86) |
| Sex | ||||||
| Male (Ref.) | 1.00 | – | – | 1.00 | – | – |
| Female | 0.86 | 0.685 | (0.42–1.76) | 0.64 | 0.299 | (0.27–1.50) |
| Age (years) | ||||||
| ≤60 (Ref.) | 1.00 | – | – | 1.00 | – | – |
| >60 | 1.00 | 0.997 | (0.45–2.23) | 1.09 | 0.866 | (0.40–2.95) |
| Stage | ||||||
| Stage I (Ref.) | 1.00 | – | – | 1.00 | – | – |
| Stage II | 1.28 | 0.657 | (0.43–3.82) | 1.56 | 0.510 | (0.42–5.84) |
| Stage III | 1.67 | 0.334 | (0.59–4.70) | 1.91 | 0.272 | (0.60–6.06) |
| Stage IVA | 5.56 | 0.001 | (2.01–15.40) | 7.73 | 0.002 | (2.17–27.51) |
| CEA (ng/mL) | ||||||
| ≤5.0 (Ref.) | 1.00 | – | – | 1.00 | – | – |
| >5.0 | 3.08 | 0.016 | (1.23–7.71) | 1.874 | 0.252 | (0.64–5.49) |
Notes: All variables were used in multivariate analysis. Group A, narrow-margin hepatectomy plus postoperative radiotherapy; Group B, narrow-margin hepatectomy alone; Group C, wide-margin hepatectomy alone.
Abbreviations: aHR, adjusted hazard ratio; HR, hazard ratio; CI, confidence interval; CEA, carcinoembryonic antigen; Ref, reference group.