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. 2018 Sep 21;9:59–78. doi: 10.2147/SAR.S150253

Table 4.

Adjusted odds of at least one indicator of relapse in the 12-month post-index period among adult patients with OUD who were newly initiating buprenorphine MATa

Effectb Commercial sample (n=16,085)
Medicaid sample (n=5,688)
OR, point estimate 95% Wald
OR, point estimate 95% Wald
Confidence limits Confidence limits
PDC: <0.20 (vs. PDC≥0.80) 2.02 1.77 2.32 1.76 1.40 2.20
PDC: 0.20≤PDC<0.40 (vs. PDC≥0.80) 2.33 1.99 2.74 1.90 1.45 2.50
PDC: 0.40≤PDC<0.60 (vs. PDC≥0.80) 2.27 1.92 2.70 1.65 1.22 2.23
PDC: 0.60≤PDC<0.80 (vs. PDC≥0.80) 1.65 1.37 1.98 1.48 1.06 2.06
Age 0.99 0.98 0.99 0.98 0.97 0.99
Female sex (vs. male) 0.97 0.87 1.08 0.87 0.72 1.07
Black race (vs. White) N/A N/A N/A 1.24 0.89 1.75
Hispanic race (vs. White) N/A N/A N/A 1.16 0.49 2.75
Other race (vs. White) N/A N/A N/A 1.52 1.06 2.18
Spouse relationship to policyholder (vs. employee) 1.01 0.86 1.19 N/A N/A N/A
Child/other relationship to policyholder (vs. employee) 2.02 1.69 2.42 N/A N/A N/A
Comprehensive/indemnity insurance plan type (vs. EPO/PPO) 1.51 1.15 2.00 N/A N/A N/A
POS/POS with capitation insurance plan type (vs. EPO/PPO) 0.90 0.76 1.07 N/A N/A N/A
HMO insurance plan type (vs. EPO/PPO) 0.99 0.86 1.14 N/A N/A N/A
CDHP/HDHP insurance plan type (vs. EPO/PPO) 0.91 0.74 1.21 N/A N/A N/A
Medicaid managed care plan type (vs. non-managed care) N/A N/A N/A 1.10 0.91 1.34
Pre-index alcohol use disorder diagnosis (vs. no) 1.22 1.05 1.42 1.18 0.90 1.56
Pre-index non-opioid drug use disorder diagnosis (vs. no) 1.30 1.17 1.45 1.41 1.17 1.71
Pre-index severe mental illness diagnosis (vs. no) 1.15 0.96 1.38 1.37 1.11 1.70
Pre-index other mental illness diagnosis (vs. no) 1.17 1.04 1.31 1.02 0.85 1.23
Pre-index chronic pain condition diagnosis (vs. no) 0.97 0.87 1.09 1.07 0.89 1.29

Notes:

a

Based on logistic regression models; examination of variance inflation factors confirmed the absence of high correlation between covariates.

b

Covariates differed for the Commercial and Medicaid models due to differences in the underlying databases used for the analysis; variables not included in a model are denoted with “N/A”.

Abbreviations: CDHP, consumer-driven health plan; EPO, exclusive provider organization; HDHP, high deductible health plan; HMO, health maintenance organization; MAT, medication-assisted treatment; OUD, opioid use disorder; PDC, proportion of days covered; POS, point of service plan; PPO, preferred provider organization; N/A, not applicable.