Table 3.
Disease activity and damage scores used in childhood Takayasu Arteritis.
| Score | Activity vs. Damage | TA-specific | Validated in pediatrics | Type of vasculitis | Highlights | References |
|---|---|---|---|---|---|---|
| NIH* | Activity | Yes | No | Large vessels |
*It is based on 3 aspects: clinical, laboratory and angiographic *Reproducibility |
(1) |
| BVAS | Activity | No | No | Small and medium vessels |
*Underestimates cardiovascular findings *Reproducibility |
(146) |
| ITAS2010 | Activity | Yes | No | Large vessels |
* It is composed of clinical features *It ranks cardiovascular findings *Reproducibility |
(150) |
| ITAS-A | Activity | Yes | No | Large vessels |
*It is composed of clinical features and acute phase markers *Reproducibility *Sensitive to change |
(150) |
| DEI-TaK | Activity | Yes | No | Large vessels | *Only a few features are represented | (149) |
| PVAS | Activity | No | Yes | Small and medium vessels | *Only a few features are represented | (151) |
| TADS | Damage | Yes | No | Large vessels | *It may be optimal for large vessels | (147) |
| PVDI | Damage | No | Yes | Small and medium vessels |
*Only a few features are represented *It may not be optimal for large vessels |
(152) |
*
Definition of activity. TA, Takayasu arteritis; NIH, National Institutes of Health; BVAS, Birmingham Vasculitis Activity Score; ITAS, Indian Takayasu Activity Score; DEI-TaK, Disease-Extent Index for Takayasu arteritis; PVAS, Pediatric Vasculitis Activity Score; TADS, Takayasu Damage Score; PVDI, Pediatric Vasculitis Damage Index.