Skip to main content
. 2018 Aug 31;5(5):846–857. doi: 10.1002/ehf2.12298

Figure 4.

Figure 4

Kaplan–Meier curves illustrate the occurrence of the primary study endpoint stratified by myocardial C3aR expression. During a mean follow‐up of 11.9 months, 36 (35.2%) patients reached the primary endpoint. Out of these, 11 (30.6%) were C3aR positive (Score 1). The primary study endpoint was defined as a composite of all‐cause death, heart transplantation, HF‐related re‐hospitalization, and deterioration of LVEF. (A) Kaplan–Meier curves illustrate in the overall patient cohort (n = 102, inflammatory and non‐inflammatory cardiomyopathy) that patients negative for C3aR (Score 0) reach the primary endpoint more often than patients, who are C3aR positive (Score 1, log rank 5.963, P = 0.015). (B) In the subgroup analysis of patients with inflammatory cardiomyopathy (n = 54), Kaplan–Meier curves demonstrate that patients negative for C3aR (Score 0) reach the primary endpoint more often than patients, who are positive for C3aR with a trend for statistical significance (Score 1, log rank 3.749, P = 0.053).