Table 1.
Results of QTL analysis.
| SNP | Gene | p-value | FDR |
|---|---|---|---|
| T-tau/Aβ42 | |||
| rs4420638 | APOC1∗ | 7.43E-29 | 4.28E-23 |
| rs769449 | APOE | 3.95E-26 | 1.14E-20 |
| rs157582 | TOMM40 | 2.69E-21 | 5.16E-16 |
| rs2075650 | TOMM40 | 2.03E-18 | 2.92E-13 |
| rs157580 | TOMM40 | 4.61E-08 | 0.0053 |
| p-tau/Aβ42 | |||
| rs4420638 | APOC1∗ | 3.09E-27 | 1.78E-21 |
| rs769449 | APOE | 5.54E-24 | 1.59E-18 |
| rs157582 | TOMM40 | 2.6E-20 | 4.99E-15 |
| rs2075650 | TOMM40 | 4.63E-17 | 6.66E-12 |
| rs157580 | TOMM40 | 1.16E-07 | 0.013402 |
| Aβ42 | |||
| rs4420638 | APOC1∗ | 9.51E-21 | 5.47E-15 |
| rs769449 | APOE | 1.11E-18 | 3.18E-13 |
| rs157582 | TOMM40 | 1.72E-15 | 3.29E-10 |
| rs2075650 | TOMM40 | 8.34E-15 | 1.2E-09 |
| ADAS13 | |||
| rs769449 | APOE | 1.88E-14 | 1.08E-08 |
| rs4420638 | APOC1∗ | 3.03E-11 | 8.73E-06 |
| rs2075650 | TOMM40 | 8.89E-09 | 0.001706 |
Only QTL results with FDR < 0.05 are shown. If the SNP is located within a gene, the gene is listed, otherwise the nearest gene is listed. ∗Nearest gene proximal to the SNP. Without this symbol means the SNP is located within the corresponding gene.