Skip to main content
. 2018 Sep 24;9:410. doi: 10.3389/fgene.2018.00410

Table 3.

Alleles distribution of the five AD-associated SNPs in four diagnostic groups.

CN (281) EMCI (235) LMCI (249) AD (47)
rs4420638 (A/G)
AA 180 (64.06%) 139 (59.15%) 115 (46.18%) 15 (31.91%)
AG 91 (32.38%) 75 (31.91%) 104 (41.77%) 23 (48.94%)
GG 10 (3.56%) 21 (8.94%) 30 (12.05%) 9 (19.15%)
MAF 19.75% 24.89% 32.93% 43.62%
rs769449 (G/A)
GG 228 (81.14%) 164 (69.79%) 145 (58.23%) 20 (42.55%)
GA 49 (17.44%) 63 (26.81%) 87 (34.94%) 22 (46.81%)
AA 4 (1.42%) 8 (3.40%) 17 (6.83%) 5 (10.64%)
MAF 10.14% 16.81% 24.30% 34.04%
rs2075650 (A/G)
AA 204 (72.60%) 154 (65.53%) 140 (56.23%) 21 (44.68%)
AG 71 (25.27%) 70 (29.79%) 95 (38.15%) 22 (46.81%)
GG 6 (2.13%) 11 (4.68%) 14 (5.62%) 4 (8.51%)
MAF 14.77% 19.57% 24.70% 31.91%
rs157582 (C/T)
CC 158 (56.23%) 123 (52.34%) 110 (44.18%) 17 (36.17%)
CT 109 (38.79%) 90 (38.30%) 110 (44.18%) 23 (48.94%)
TT 14 (4.98%) 22 (9.36%) 29 (11.64%) 7 (14.89%)
MAF 24.38% 28.51% 33.73% 39.36%
rs157580 (A/G)
AA 104 (37.01%) 105 (44.68%) 115 (46.18%) 19 (40.43%)
AG 136 (48.40%) 100 (42.55%) 109 (43.78%) 24 (51.06%)
GG 41 (14.59%) 30 (12.77%) 25 (10.04%) 4 (8.51%)
MAF 38.79% 34.04% 31.93% 34.04%

(/) The first allele is major allele while the second one is minor allele.