Table 2.
Characteristics of infants on the basis of CPI
| Variable | Non-CPI (n = 312) | CPI (n = 90) | p-value |
|---|---|---|---|
| Gestational age (wk) | 29.1 ± 2.9 | 28.4 ± 3.2 | .007* |
| Birth weight (g) | 1,064.7 ± 286.9 | 1,012.5 ± 309.1 | .589 |
| Sex | .506 | ||
| Male | 154 (49.3) | 48 (53.3) | |
| Female | 158 (50.6) | 42 (46.7) | |
| Pre-eclampsia | 78 (25.0) | 9 (10.0) | .031* |
| Antenatal steroid use | 284 (91.0) | 79 (87.8) | .398 |
| IUGR | 107 (34.3) | 26 (28.9) | .338 |
| RDS | 177 (56.7) | 61 (67.8) | .068 |
| Significant PDA | 127 (40.7) | 40 (44.4) | .531 |
| Moderate to severe BPD | 79 (25.3) | 26 (28.9) | .497 |
| Postnatal steroid therapy | 72 (23.1) | 24 (26.7) | .496 |
| Duration of oxygen supply (day) | 41.4 ± 38.2 | 41.0 ± 38.1 | .163 |
| Severe neurologic injury (IVH ≥ grade 3 or PVL) | 34 (10.9) | 9 (10) | .051 |
| NEC (≥ stage 2) | 15 (4.8) | 4 (4.4) | .882 |
| LOS | 65 (20.8) | 23 (25.6) | .164 |
| ROP (any stage) | 71 (22.8) | 26 (28.9) | .021* |
| Type 1 ROP | 27 (8.6) | 19 (21.1) | .003* |
| Hospital days (day) | 66.5 ± 36.0 | 72.6 ± 36.1 | .154 |
Values are presented as mean ± SD or number (%).
CPI, chronic placental inflammation; IUGR, intrauterine growth retardation; RDS, respiratory distress syndrome; PDA, patent ductus arteriosus; BPD, bronchopulmonary dysplasia; IVH, intraventricular hemorrhage; PVL, periventricular leukomalacia; NEC, necrotizing enterocolitis; LOS, late-onset sepsis; ROP, retinopathy of prematurity; SD, standard deviation.
*
p < .05.