Table 4.
Associations of LOX expression with clinicopathologic characteristics
| Clinicopathological parameter | LOX expression |
p-value | |
|---|---|---|---|
| Absent | Present | ||
| Age (yr) | |||
| < 60 | 43 (42.6) | 58 (57.4) | .392 |
| ≥ 60 | 50 (48.5) | 53 (51.5) | |
| Sex | |||
| Male | 61 (43.9) | 78 (56.1) | .475 |
| Female | 32 (49.2) | 33 (50.8) | |
| Tumor size (cm) | |||
| ≤ 7 | 77 (45.8) | 91 (54.2) | .879 |
| > 7 | 16 (44.4) | 20 (55.6) | |
| Fuhrman nuclear grade | |||
| Low (grade 1 and 2) | 56 (43.1) | 74 (56.9) | .209 |
| High (grade 3 and 4) | 37 (50.0) | 37 (50.0) | |
| Pathologic stage | |||
| Low (stage 1 and 2) | 77 (44.5) | 96 (55.5) | .295 |
| High (stage 3 and 4) | 16 (51.6) | 15 (48.4) | |
| Lymphovascular invasion | |||
| Absent | 76 (43.4) | 99 (56.6) | .128 |
| Present | 17 (58.6) | 12 (41.4) | |
| Tumor necrosis | |||
| Absent | 80 (47.3) | 89 (52.7) | .270 |
| Present | 13 (37.1) | 22 (62.9) | |
| Intratumoral inflammation | |||
| Absent | 7 (5.3) | 126 (94.7) | .911 |
| Present | 4 (5.6) | 67 (94.4) | |
| Intratumoral fibrosis | |||
| Absent | 16 (43.2) | 21 (56.8) | .752 |
| Present | 77 (46.1) | 90 (53.9) | |
Values are presented as number (%).
LOX, lysyl oxidase.