Table 1.
Clinical and neuropsychological characteristics at baseline in pre-mild cognitive impairment subgroups*
| preMCIcon | preMCInoncon | p-value | |
|---|---|---|---|
| N | 13 | 27 | |
| Age (SD), y† | 75.54 (4.63) | 72.67 (3.93) | 0.048 |
| Education (SD), y | 12.08 (4.65) | 10.30 (4.30) | 0.240 |
| Female, N | 6 | 21 | 0.072 |
| SMC | 3.31 (2.78) | 4.63 (3.38) | 0.229 |
| IADL | 0.12 (0.14) | 0.10 (0.13) | 0.547 |
| GDS | 6.54 (4.65) | 8.19 (5.40) | 0.352 |
| MMSE | -0.18 (0.75) | 0.04 (0.71) | 0.376 |
| Attention | |||
| DSF | -0.44 (1.27) | 0.62 (1.00) | 0.627 |
| DSB | 0.20 (1.55) | 0.37 (0.93) | 0.661 |
| Language | |||
| BNT | 0.37 (0.82) | 0.30 (0.93) | 0.811 |
| Visuospatial functions | |||
| RCFT copy | 0.31 (0.60) | 0.51 (0.44) | 0.256 |
| Memory | |||
| SVLT_imm | -0.18 (0.38) | 0.15 (1.03) | 0.267 |
| SVLT_delayed | -0.29 (0.67) | 0.22 (1.06) | 0.124 |
| SVLT_rec† | -0.30 (0.91) | 0.39 (0.79) | 0.018 |
| RCFT_imm | -0.05 (1.03) | 0.24 (0.91) | 0.357 |
| RCFT_delayed† | -0.12 (0.64) | 0.37 (0.73) | 0.042 |
| RCFT_rec | 0.01 (0.81) | 0.34 (0.76) | 0.202 |
| Executive functions | |||
| Fluency_A | -0.03 (0.83) | 0.04 (0.75) | 0.783 |
| Fluency_P | -0.32 (0.97) | 0.27 (0.83) | 0.055 |
| Stroop | 0.04 (0.89) | 0.40 (0.91) | 0.250 |
| TMT_A | -0.02 (0.53) | 0.29 (0.52) | 0.089 |
| TMT_B | 0.36 (0.67) | 0.24 (0.60) | 0.585 |
neuropsychological data presented as group mean z-scores based on age-, education-, and gender specific normative information (standard deviation),
significant group-difference.
pre-MCIcon: pre-mild cognitive impairment group who converted to mild cognitive impairment, pre-MCInoncon: pre-mild cognitive impairment group who did not convert to MCI, SMC: subjective memory complaints, IADL: instrumental activities of daily living, GDS: geriatric depression scale, DSQ: dementia screening questionnaire, MMSE: mini mental status examination, DSF: digit span forward, DSB: digit span backward, BNT: Boston naming test (15 item), RCFT copy: Rey complex figure test copy score, SVLT_imm: Seoul verbal learning test, immediate recall score, SVLT_delayed: SVLT, delayed recall score, SVLT_rec: SVLT, recognition score, RCFT_imm: RCFT, immediate recall score, RCFT_delayed: RCFT, delayed recall score, RCFT_rec: RCFT, recognition score, Fluency_A: fluency score for animal, Fluency_P: fluency score for 3 Korean alphabet, Stoop: Stroop score for color naming in color-word in incongruent condition, TMT: trail making test