Table 1.
Demographic and clinical characteristics of subjects, according to serum uric acid levels
| Characteristic | UA grading* |
P-value† | |||
|---|---|---|---|---|---|
| Total (N=5,093) | T1 (n=1,755) | T2 (n=1,628) | T3 (n=1,710) | ||
| Uric acid (mg/dL) | 3.8±0.6 (0.9–4.6) | 5.3±0.4 (4.7–5.9) | 7.0±0.9 (6.0–11.6) | ||
| Age (y) | 50.7±10.4 | 50.8±10.6 | 51.6±10.2 | 49.7±10.3 | <0.001 |
| Male | 3,052 (59.9) | 412 (23.5) | 1,038 (63.8) | 1,602 (93.7) | <0.001 |
| Body mass index (kg/m2) | 24.0±3.2 | 22.8±3.0 | 23.8±2.9 | 25.2±3.0 | <0.001 |
| Systolic blood pressure (mm Hg) | 118±14 | 116±15 | 118±15 | 121±14 | <0.001 |
| Diastolic blood pressure (mm Hg) | 75±11 | 73±10 | 75±11 | 78±10 | <0.001 |
| Total glyceride (mg/dL) | 122.8±88.0 | 99.2±64.0 | 120.4±84.9 | 149.3±103.7 | <0.001 |
| High-density lipoprotein cholesterol (mg/dL) | 55.4±14.5 | 60.2±14.6 | 55.6±14.8 | 50.2±12.2 | <0.001 |
| Low-density lipoprotein cholesterol (mg/dL) | 122.7±34.3 | 119.3±32.8 | 123.6±34.2 | 125.7±35.5 | <0.001 |
| Fasting plasma glucose (mg/dL) | 98.3±20.5 | 98.0±24.3 | 98.1±19.8 | 98.8±16.6 | 0.560 |
| Hemoglobin A1c (%) | 5.6±0.8 | 5.9±1.0 | 5.7±0.7 | 5.7±0.7 | 0.266 |
| Diabetes mellitus | 326 (6.4) | 135 (7.7) | 109 (6.7) | 82 (4.8) | 0.093 |
| Hypertention | 1,119 (22.0) | 300 (17.1) | 377 (23.2) | 442 (25.8) | 0.001 |
| Dyslipidemia | 951 (18.7) | 281 (16.0) | 329 (20.2) | 341 (19.9) | 0.001 |
| Current smokers | 995 (19.5) | 146 (8.3) | 334 (20.5) | 515 (30.1) | <0.001 |
| Drinking alcohol | 2,813 (55) | 683 (38.9) | 911 (56.0) | 1,219 (71.3) | <0.001 |
| Derivatives of reactive oxygen metabolites (Carr units) | 346.6±1.2 | 352.3±1.2 | 346.2±1.2 | 338.5±1.2 | 0.009 |
| Biological antioxidant potential (µM) | 2,181.6±1.1 | 2,107.0±1.1 | 2,178.7±1.1 | 2,239.7±1.1 | <0.001 |
Values are presented as mean±standard deviation (range), mean±standard deviation, or number (%).
*
T1, 1st tertile; T2, 2nd tertile; T3, 3rd tertile.
†
One-way analysis of variance, P<0.05.