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. 2018 Aug 7;37(19):e94813. doi: 10.15252/embj.201694813

Figure EV3. FLNA editing‐deficient vascular smooth muscle cells show mislocalization of p190Rho GAP .

Figure EV3

  1. Representative images of wild‐type (wt) and FLNAΔECS vascular smooth muscle cells (vSMCs) stained with P190RhoGAP antibody (green) before and after treatment with 1 μM U46619. Note the change in localization in wt cells after U46619 treatment that looks similar to the untreated cells expressing only unedited FLNA. Scale bar: 20 μm.
  2. Quantification of subcellular localization of p190RhoGAP in wt and FLNAΔECS vSMCs. Graphs are plotted as percentage of cells showing membranous vs. cytoplasmic localization. Data were pooled after counting 250–300 cells in each condition.

Source data are available online for this figure.